Neil Redfearn has made two changes to his Leeds United side as they go in search of four straight away wins for the first time in almost 14 years.
Liam Cooper replaces the suspended Giuseppe Bellusci at the back, while Casper Sloth makes just his seventh league start of the season in place of Sam Byram.
Hosts Brighton, meanwhile, have one change in their XI to the side that outlasted Birmingham City 4-3 in Saturday's thriller at The Amex.
It comes up front as Craig Mackail-Smith gets the nod over Leon Best.
Brighton: Stockdale; Bruno, Greer, Dunk, Bennett; Ince, Kayal, Calderon, Teixeira, Baldock; Mackail-Smith
Subs: Walton, Hughes, Ledesma, Lua Lua, Stephens, Best, O'Grady
Leeds: Silvestri; Wootton, Bamba, Cooper, Taylor; Sloth, Cook, Murphy, Austin, Mowatt; Morison
Subs: Taylor, Berardi, Del Fabro, Antenucci, Cani, Doukara, Sharp