Eddie Jones has made a total of four alterations to his England team for Saturday's Six Nations encounter with Wales.
The two nations have each suffered one defeat from their opening two fixtures, but England hold the advantage of having claimed two bonus points ahead of the showdown at Twickenham.
Despite posting a 33-0 victory over Italy in Rome, several fresh faces have been brought into the team, including Courtney Lawes who will captain the side after completing concussion protocols.
Manu Tuilagi is also a notable inclusion having recovered from a hamstring injury, while hooker Luke Cowan-Dickie takes the spot of Jamie George.
Kyle Sinckler, a half-time replacement for Will Stuart last time out, is the fourth and final change, making his 50th appearance in the process.
England team in full: Steward; Malins, Slade, Tuilagi, Nowell; Smith, Randall; Genge, Cowan-Dickie, Sinckler, Ewels, Itoje, Lawes (Capt), Curry, Dombrandt.
Replacements: George, Marler, Stuart, Isiekwe, Simmonds, Youngs, Ford, Daly