Laurent Fournier makes one change to the side that lost 2-1 to Caen on Wednesday.
Roy Contout has been sacrificed for the sake of Prince Segbefia, who joins Dennis Oliech and Delvin Ndinga in the attack.
Meanwhile, Saint-Etienne make three changes from Wednesday's 4-2 win at home to Lorient FC.
Faouzi Ghoulam, Joshua Guilavogui and ex-Leeds star Max Gradel come in for Laurent Battles, Fabien Lemoine and Jonathan Brison.
Auxerre: Olivier Sorin; Cedric Hengbart, Willy Boly, Stephane Grichting (c); Dariusz Dudka, Edouard Cisse, Olivier Kapo, Georges Mandjeck; Prince Segbefia, Delvin Ndinga, Dennis Oliech
Saint-Etiennt: Stephane Ruffier; Sylvain Marchal, Albin Ebondo, Jean-Pascal Mignot; Faouzi Ghoulam, Jeremy Clement, Joshua Guilavogui, Banel Nicolita Bakary Sako, Max Gradel; Pierre-Emerick Aubamyang
