The AC Milan midfielder has been replaced in the squad by PSV Eindhoven forward Luuk de Jong.
Meanwhile, Queens Park Rangers's Leroy Fer has been called up by manager Guus Hiddink as a replacement for the injured Davy Klaassen.
The Dutch host Mexico in a friendly on Wednesday before entertaining Latvia four days later in a Euro 2016 qualifier.
Restore Data
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Liverpool | 6 | 5 | 0 | 1 | 12 | 2 | 10 | 15 |
| 2 | Manchester CityMan City | 6 | 4 | 2 | 0 | 14 | 6 | 8 | 14 |
| 3 | Arsenal | 6 | 4 | 2 | 0 | 12 | 5 | 7 | 14 |
| 4 | Chelsea | 6 | 4 | 1 | 1 | 15 | 7 | 8 | 13 |
| 5 | Aston Villa | 6 | 4 | 1 | 1 | 12 | 9 | 3 | 13 |
| 6 | Fulham | 6 | 3 | 2 | 1 | 8 | 5 | 3 | 11 |
| 7 | Newcastle UnitedNewcastle | 6 | 3 | 2 | 1 | 8 | 7 | 1 | 11 |
| 8 | Tottenham HotspurSpurs | 6 | 3 | 1 | 2 | 12 | 5 | 7 | 10 |
| 9 | Brighton & Hove AlbionBrighton | 6 | 2 | 3 | 1 | 10 | 8 | 2 | 9 |
| 10 | Nottingham ForestNott'm Forest | 6 | 2 | 3 | 1 | 6 | 5 | 1 | 9 |
| 11 | Bournemouth | 6 | 2 | 2 | 2 | 8 | 9 | -1 | 8 |
| 12 | Brentford | 6 | 2 | 1 | 3 | 8 | 10 | -2 | 7 |
| 13 | Manchester UnitedMan Utd | 6 | 2 | 1 | 3 | 5 | 8 | -3 | 7 |
| 14 | West Ham UnitedWest Ham | 6 | 1 | 2 | 3 | 6 | 10 | -4 | 5 |
| 15 | Ipswich TownIpswich | 6 | 0 | 4 | 2 | 5 | 10 | -5 | 4 |
| 16 | Everton | 6 | 1 | 1 | 4 | 7 | 15 | -8 | 4 |
| 17 | Leicester CityLeicester | 6 | 0 | 3 | 3 | 8 | 12 | -4 | 3 |
| 18 | Crystal Palace | 6 | 0 | 3 | 3 | 5 | 9 | -4 | 3 |
| 19 | Southampton | 6 | 0 | 1 | 5 | 3 | 12 | -9 | 1 |
| 20 | Wolverhampton WanderersWolves | 6 | 0 | 1 | 5 | 6 | 16 | -10 | 1 |
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