Seeking to spark a phenomenal turnaround against this season's Champions League comeback kings, Chelsea visit the Bernabeu for the second leg of their European quarter-final on Tuesday night.
The defending champions head to the Spanish capital after being sunk 3-1 in the first leg at Stamford Bridge, with one illustrious Frenchman doing the damage on the night as either Manchester City or Atletico Madrid lie in wait in the semi-finals.
Match preview
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There are not enough superlatives in the dictionary to describe Real Madrid number nine Karim Benzema, who played second fiddle to Cristiano Ronaldo for so long at the Bernabeu but is now stealing the spotlight as Los Blancos seek domestic and continental glory.
As if one hat-trick to dump Paris Saint-Germain out of the competition was not enough, Benzema made it back-to-back European trebles with an extraordinary showing at Stamford Bridge - scoring two early headers with the aplomb of the seasoned centre-forward that he is before taking home the match ball after Edouard Mendy's uncharacteristic mistake.
Carlo Ancelotti's side have one foot firmly in the semi-finals of this year's competition and also ensured that they retained their double-figure advantage over the chasing pack in La Liga with a straightforward 2-0 success over Getafe - their eighth victory from nine in all competitions.
Los Blancos have certainly proven that the 4-0 Clasico thumping at the hands of Barcelona was little more than an outlier, and only once in 10 previous occasions have they failed to make it through in the Champions League when winning the first leg away from home - Ajax still rings a bitter bell for some Bernabeu supporters.
A second successive semi-final appearance is now within Real Madrid's sights, and they have struck at least two goals in each of their last three Champions League wins on home soil, but Chelsea did manage to respond with a goal-laden showing of their own on the South Coast.
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The defence of their crown is seemingly in tatters after such a catastrophic first-leg loss, but Kai Havertz's header has at least given Chelsea a slight glimmer of hope, with the German coming up clutch in the big games for the Blues once again.
In dire need of a response to home defeats to Los Blancos and Brentford, Tuchel got the reaction that he was hoping for against Southampton, whose error-strewn performance ended in a 6-0 hammering at the hands of Mason Mount (2), Timo Werner (2), Marcos Alonso and Havertz, and the only consolation Southampton supporters could take from that 6-0 loss is that it did not end up being nine.
Tuchel could hardly have asked for a better warm-up for the trip to the Bernabeu, where they will have to pull off a feat that no English team has ever done before if they are to remain alive in the competition - win at the ground by at least two goals.
In spite of their recent collapses at Stamford Bridge, the demolition job at St Mary's represented Chelsea's seventh win away from home in all competitions, and they have only failed to score in one of their last 15 Champions League games in which they were billed as the away team.
Victory over the Blues at Stamford Bridge saw Real Madrid end a five-match winless hoodoo against the London club in European competition, and the pressure is now on Ancelotti's men to avoid suffering what they inflicted on PSG only a few weeks ago.
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Team News
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Real Madrid centre-back Eder Militao was fine to play the full 90 at the weekend despite coming off at Stamford Bridge, but the Brazilian will be watching from the naughty step this week as he serves a suspension for an accumulation of yellow cards.
Former Chelsea man Eden Hazard remains in the treatment room alongside Isco, but backup striker Luka Jovic has shaken off an ankle injury and centre-back Jesus Vallejo is absent after contracting COVID-19.
Ferland Mendy was rested at the weekend and should be fine to take Marcelo's place at left-back, while Nacho Fernandez should deputise for the suspended Militao, and Toni Kroos and Luka Modric are both refreshed after watching the win against Getafe from the substitutes' bench.
Chelsea have a similar number of fitness concerns to deal with ahead of the second leg, with long-term absentee Ben Chilwell definitely out alongside Callum Hudson-Odoi, who has suffered a setback in his recovery from an Achilles issue.
Romelu Lukaku also missed the win at Southampton with Achilles pain and will sit out the Bernabeu trip, but Cesar Azpilicueta has tested negative for COVID-19 and is set to make the journey. However, Ross Barkley is now sick himself and is absent.
Tuchel was able to bring Havertz, Mount and Thiago Silva off early at St Mary's, but Werner's brace may not be enough to see him retain his spot over Hakim Ziyech or Christian Pulisic.
Real Madrid possible starting lineup:
Courtois; Carvajal, Nacho, Alaba, Mendy; Kroos, Casemiro, Modric; Asensio, Benzema, Vinicius Jr
Chelsea possible starting lineup:
Mendy; Christensen, Silva, Rudiger; James, Kovacic, Kante, Alonso; Ziyech, Mount; Havertz
We say: Real Madrid 2-2 Chelsea (Real Madrid win 5-3 on aggregate)
Having rediscovered their golden touch against a lacklustre Southampton, Chelsea have already shown that they can breach this Real Madrid backline and will fancy their chances of doing so on more than one occasion with an attack-minded approach and no Militao in the hosts' lineup.
Tuchel's side simply have to go for goals in the Spanish capital, but such an approach will always leave them susceptible to Vinicius Junior's dynamism and Benzema's brilliance on the break, and Real can nick a couple goals of their own to end Chelsea's dreams of back-to-back European titles.
Top tip
Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Chelsea win with a probability of 38.67%. A win for Real Madrid had a probability of 37.83% and a draw had a probability of 23.5%.
The most likely scoreline for a Chelsea win was 1-2 with a probability of 8.41%. The next most likely scorelines for that outcome were 0-1 (6.64%) and 0-2 (5.32%). The likeliest Real Madrid win was 2-1 (8.31%), while for a drawn scoreline it was 1-1 (10.5%).