Nemanja Vidic, Nani and Antonio Valencia are all expected to return to action when Manchester United face Crewe Alexandra in a pre-season friendly on Monday.
United skipper Vidic, who has been suffering from sciatica, is expected to lead the team out, while Portuguese winger Nani will return after missing the pre-season tour of Asia with a nasal problem.
Valencia is also yet to feature for the first team this summer due to international commitments with Ecuador, but the trio will all return for the friendly at Gresty Road.
Federico Macheda and Bebe are also expected to feature for the Premier League champions.
