Matthew Rees will miss Wales's Six Nations opener against Ireland this weekend with a calf injury.
The former skipper sustained the problem during a training session and as a result will miss the next two weeks.
That means he will also miss the fixture against Scotland in a fortnight's time.
Rees has joined an injury list that includes Gethin Jenkins, Lloyd Burns, Luke Charteris, Alun-Wyn Jones and Jamie Roberts.