Southampton vs. Brighton (Sunday, 12.00pm)
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Brighton & Hove Albion will be looking to bring an end to their losing run and ease their relegation concerns when they travel to South Coast rivals Southampton on Sunday.
The Seagulls have lost three in a row and are level on points with the bottom three, while Southampton have also been on a poor run but are seven points better off in 14th.
We say: Southampton 1-1 Brighton & Hove Albion
Brighton need to quickly arrest their slump if they are to remain above the relegation zone following a run of three losses in a row and no win in five.
The Saints have also struggled for victories in 2021, winning just one of their last 11 league matches, and could be dragged into a relegation scrap with defeat on Sunday.
All three of Brighton's Premier League games at St Mary's have finished level, and we can see this latest contest between the sides ending the same way.
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> How Southampton could line up against Brighton
> How Brighton could line up against Southampton
Leicester vs. Sheff Utd (Sunday, 2.00pm)
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Leicester City will be looking to tighten their grip on a top-four spot in the Premier League when they face bottom side Sheffield United at the King Power Stadium on Sunday.
The Foxes returned to winning ways last time out and are five points clear of fifth, while United are destined for relegation and are on the verge of sacking manager Chris Wilder.
We say: Leicester City 2-0 Sheffield United
Any slim hopes United had of pulling off a great escape were ended with last week's home loss against Southampton.
The Blades are now effectively playing for pride, whereas Leicester have plenty on the line ahead of this game.
City may not have performed all that well at the King Power Stadium this term, but we can only see one outcome on Sunday.
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> How Sheff Utd could line up against Leicester City
> How Leicester could line up against Sheff Utd
Arsenal vs. Spurs (Sunday, 4.30pm)
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One of the standout fixtures in the Premier League calendar will take place at the Emirates Stadium on Sunday afternoon as Arsenal welcome Tottenham Hotspur for the North London derby.
Arsenal are currently 10th in the table, having picked up just 38 points from 27 matches this season, while Tottenham occupy seventh, five points behind fourth-placed Chelsea with a game in hand.
We say: Arsenal 1-1 Tottenham Hotspur
Mourinho has lost just two of his 22 matches as a manager against Arsenal, and we are struggling to see a home victory in this match. Arsenal have certainly shown improvement in recent weeks, though, and they are more than capable of making it a tough afternoon for their bitter rivals. We are expecting a close match at the Emirates Stadium and have ultimately settled on a low-scoring draw.
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> How Tottenham could line up against Arsenal
> How Arsenal could line up against Tottenham
> Tottenham injury, suspension list vs. Arsenal
> Combined XI: Arsenal vs. Tottenham Hotspur
Man Utd vs. West Ham (Sunday, 7.15pm)
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One of the standout fixtures in the latest round of Premier League matches will take place at Old Trafford on Sunday night as Manchester United welcome West Ham United to Old Trafford.
Man United are currently second in the table, 14 points behind leaders Manchester City, while the Red Devils sit six points clear of fifth-placed West Ham, who are firmly in the hunt for a top-four spot.
We say: Manchester United 1-1 West Ham United
This is a very, very difficult game for Man United, particularly considering the home team's injury problems. West Ham are now a side to be taken extremely seriously at the top end of the Premier League table, and we can see the Hammers holding Solskjaer's team to a low-scoring draw at Old Trafford.
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> How West Ham could line up against Man United
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