Although City's injury issues have eased in recent weeks, the Spaniard still faces the prospect of being without a number of first-team players for the clash at the Etihad Stadium.

Here, Sports Mole rounds up City's latest injury and suspension news ahead of squaring off against their most likely title rivals.

Sergio Aguero

Manchester City striker Sergio Aguero in action on October 17, 2020 © Reuters

Status: Major doubt
Type of injury: Hamstring
Possible return date: November 8 (vs. Liverpool)

Aguero is currently nursing a hamstring problem - sustained in City's draw with West Ham United - and the Argentine has missed the last three matches. Although the forward is likely to return after the international break, he is yet to be ruled out of Sunday's match.

Fernandinho

Manchester City midfielder Fernandinho walks off the pitch after picking up an injury against Porto on October 21, 2020 © Reuters

Status: Out
Type of injury: Leg
Possible return date: November 21 (vs. Tottenham Hotspur)

Fernandinho was forced off with a leg problem in City's opening 2020-21 Champions League game against Porto. The veteran will not take to the field for Guardiola's men until after the next international break.

Benjamin Mendy

Status: Out
Type of injury: Muscle
Possible return date: November 21 (vs. Tottenham Hotspur)

Like the Brazilian, a recent injury is expected to keep Mendy out until later this month. Given the players at his disposal, Guardiola will see little reason to take any risks on the left-back.