Jack Collison and Andy King are both major doubts for Wales's Euro 2012 qualifier against Switzerland on Friday through injury.
West Ham midfielder Collison has picked up a knee problem, while Leicester City midfielder King has a back injury.
Manager Gary Speed is already without Joe Ledley, James Collins, Danny Collins, Danny Gabbidon and Rob Earnshaw for the match at Swansea's Liberty Stadium.
Wales are bottom of Group G and can not qualify for next year's tournament, but third place is still a possibility, should results go their way.
