Cesc Fabregas is the only Spain survivor from their last outing as he earns his 100th cap for the national side against Ukraine this evening.

The Chelsea midfielder starts in a side that includes two debutants, with Mario Gaspar and Xabier Etxeita given their maiden bows for La Roja in Kiev.

There is also a place in the starting lineup for Paco Alcacer who, fresh on the back of scoring twice against Luxembourg last time out, joins Isco and Nolito up top in a 4-3-3 formation.

Hosts Ukraine, who can still finish second in Group C, are without suspended duo Yevhen Khacheridi and Serhiy Sydorchuk for the crucial clash at the Olympic Stadium.

Ukraine: Pyatov; Fedetskiy, Kucher, Rakitskiy, Shevchuk; Stepanenko, Rotan, Garmash; Yarmolenko, Kravets, Konoplyanka

Spain: De Gea; Mario, Etxeita, Nacho, Azpilicueta; San Jose, Fabregas, Thiago; Isco, Alcacer, Nolito

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