Colorado Rapids have lost for the fifth match running, this time away at Real Salt Lake.
Oscar Pareja's team, who failed to record a single shot on target at Rio Tinto Stadium, fell behind just after the half-hour mark.
Fabian Espindola found Alvaro Saborio in space and the Costa Rica international coolly finished from close range.
Despite their dominance, Salt Lake had to wait until second-half stoppage time to double their lead.
On this occasion Saborio provided the assist and Will Johnson did the honours.