Tottenham Hotspur will endeavour to maintain their perfect start to the 2021-22 Premier League season when they take on Crystal Palace at Selhurst Park on Saturday lunchtime.

Nuno Espirito Santo's side have marched to three consecutive 1-0 victories over Manchester City, Wolverhampton Wanderers and Watford so far, with Son Heung-min scoring the winner against the latter just before the international break.

The Lilywhites have stormed to the top of the rankings as the only team with maximum points so far, while they are also the only team in the division yet to concede ahead of gameweek four.

Here, Sports Mole rounds up all of Tottenham's latest injury and suspension news ahead of the contest.

Son Heung-min

Tottenham Hotspur's Son Heung-min celebrates after the match on August 8, 2021 © Reuters

Status: Out
Type of injury: Calf
Possible return date: Unknown

Star attacker Son Heung-min sustained a calf injury while on international duty with South Korea and missed their midweek win over Lebanon. The 29-year-old's problem will need to be assessed, but Santo has been pessimistic over his potential layoff.

Tanguy Ndombele

Tanguy Ndombele pictured for Tottenham Hotspur in April 2021 © Reuters

Status: Out
Type of injury: Other
Possible return date: Unknown

Tanguy Ndombele has been frozen out of the team by Santo but did not secure a move away in the most recent transfer window. With the midfielder still on the books at Spurs, it remains to be seen if he will be reintegrated back into the fold.

Joe Rodon

Joe Rodon pictured for Wales in October 2020 © Reuters

Status: Minor doubt
Type of injury: Thigh
Possible return date: September 11 (vs. Crystal Palace)

Joe Rodon's thigh injury did not prevent him from linking up with the Wales squad during the international break, and the defender could be in contention for the weekend after returning to full training.

Davinson Sanchez

Tottenham Hotspur's Davinson Sanchez pictured in action in October 2020 © Reuters

Status: Out
Type of injury: Other
Possible return date: September 19 (vs. Chelsea)

Davinson Sanchez is one of three players in hot water with Spurs after electing to link up with Colombia for the international break. The defender has been released from his national squad, but quarantine measures will prevent him from featuring this weekend.

Giovani Lo Celso

Argentina's Giovani Lo Celso in action at the Copa America on June 14, 2021 © Reuters

Status: Out
Type of injury: Other
Possible return date: September 19 (vs. Chelsea)

Giovani Lo Celso was one of four Argentinian players targeted by Brazilian health authorities after allegedly failing to self-isolate upon arrival from the UK - which came to a head during their World Cup qualifying battle with the Selecao - and the midfielder will miss this game.

Cristian Romero

Cristian Romero in action for Argentina in June 2021 © Reuters

Status: Out
Type of injury: Other
Possible return date: September 19 (vs. Chelsea)

Cristian Romero was also at the centre of the Argentina-Brazil debacle alongside his teammate Lo Celso, and the defender will play no part against Palace as he self-isolates.

Ryan Sessegnon

Ryan Sessegnon pictured for England Under-21s in October 2020 © Reuters

Status: Major doubt
Type of injury: Knock
Possible return date: September 11 (vs. Crystal Palace)

Ryan Sessegnon was forced to withdraw from the England Under-21s squad due to a knock and is facing a race against time to recover for the clash with Palace.