Manchester City's quest for a first Champions League trophy resumes on Wednesday with a trip to Real Madrid for the first leg of their last-16 tie.

The Citizens were rocked by news of a two-year ban from European competitions earlier this month, but it has been business as usual on the field with back-to-back wins.

Those victories over West Ham United and Leicester City have strengthened their grip on second place in the Premier League, with focus now switching to the huge midweek clash at the Santiago Bernabeu.

Here, Sports Mole rounds up City's latest injury and suspension news ahead of the last-16 first leg in Spain.

Leroy Sane

Manchester City's Leroy Sane hobbles off during the Community Shield on August 4, 2019. © Reuters

Status: Out
Type of injury: Knee
Possible return date: Unknown

Having recently spent time training with the rest of his teammates, Leroy Sane is believed to be closing in on a return from a serious knee injury. The German winger is lacking fitness, however, and Guardiola will not throw him straight into the mix for this huge match.

Raheem Sterling

Status: Minor doubt
Type of injury: Hamstring
Possible return date: February 26 (vs. Real Madrid)

Raheem Sterling injured his hamstring against Tottenham Hotspur three weeks ago and sat out the wins over West Ham and Leicester. However, Guardiola confirmed after the most recent of those victories that the England international is likely to be fit to play a part at the Santiago Bernabeu.

Aymeric Laporte

Status: Minor doubt
Type of injury: Knock
Possible return date: February 26 (vs. Real Madrid)

Aymeric Laporte hobbled off the field with an hour played at the King Power Stadium after picking up a knock. Guardiola played down the severity of the injury and Laporte, who has only recently returned from a long-term layoff, has a good chance of being fit to start.