Liverpool manager Brendan Rodgers has kept faith with the side that beat Stoke City 1-0 in their Premier League opener ahead of their home game against Bournemouth.
Big-money summer signing Christian Benteke leads the line for the hosts, while youngsters Jordon Ibe and Joe Gomez are once again preferred to the likes of Roberto Firmino and Alberto Moreno.
Meanwhile, Cherries boss Eddie Howe has made two changes to his starting XI, as Eunan O'Kane and Max Gradel start in place of Dan Gosling and Marc Pugh.
The South Coast side, in the top flight for the first time in their history, began life in the Premier League with a narrow defeat against Aston Villa.
Liverpool: Mignolet; Clyne, Lovren, Skrtel, Gomez; Henderson, Milner, Coutinho, Lallana, Ibe; Benteke
Subs: Bogdan, Toure, Firmino, Moreno, Can, Origi, Ings
Bournemouth: Boruc; Francis, Elphick, Cook, Daniels; Ritchie, O'Kane, Surman, Gradel; King, Wilson
Subs: Federici, Smith, Distin, Mings, Gosling, Pugh, Tomlin
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