Liverpool vs. Newcastle (Saturday, 12.30pm)
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Liverpool will aspire to get their charge for a top-four Premier League finish back on track when they play host to Newcastle United at Anfield on Saturday lunchtime.
The Reds dropped two points in a 1-1 draw at Leeds United last time out, while Newcastle's upturn in fortunes continued with a 3-2 win over top-four chasing West Ham United.
We say: Liverpool 2-1 Newcastle United
Newcastle are enjoying a hot streak at the perfect time for Bruce as he bids to steer them clear of the dreaded trapdoor, but they remain suspect at the back with three key defensive players nursing injuries.
The loss of Saint-Maximin would be a killer blow to their attacking prowess, and while Anfield is not the fortress that it once was, a well-rested Salah and his teammates will hope to march to another three points against the Magpies.
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> How Newcastle could line up against Liverpool
> How Liverpool could line up against Newcastle
> Liverpool injury, suspension list vs. Newcastle
West Ham vs. Chelsea (Saturday, 5.30pm)
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West Ham United prepare to play host to Chelsea in Saturday's Premier League clash, and there is much more than just capital bragging rights on the line in this London derby.
The Blues reclaimed their place in the top four of the table with a goalless stalemate against Brighton & Hove Albion on Tuesday, while West Ham are now in fifth but only behind their upcoming opponents on goal difference.
We say: West Ham United 1-1 Chelsea
West Ham have been hit with injuries and suspensions at the worst time possible, but this should still be a fascinating battle between one of the best home teams in the league and Tuchel's away-day specialists.
The Blues have only managed to win one of their last four league games as FA Cup and Champions League fatigue catches up to them, and with West Ham boasting a respectable home record against their London rivals, we expect this clash to finish all square in a result that will not do much good for either's side's top-four hopes.
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> How Chelsea could line up against West Ham
> How West Ham could line up against Chelsea
> Chelsea injury, suspension list vs. West Ham
Sheff Utd vs. Brighton (Saturday, 8.00pm)
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Brighton & Hove Albion travel to already-relegated Sheffield United on Saturday evening knowing that they can all but secure Premier League safety with a victory.
The Seagulls held Chelsea last time out and are seven points clear of the dropzone with a game in hand, while United's fate was sealed with defeat to Wolverhampton Wanderers.
We say: Sheffield United 0-1 Brighton & Hove Albion
The only real target for Sheffield United to aim for between now and the end of the season is to avoid being relegated with a Premier League record number of defeats.
Brighton are all but assured of safety but could do with another victory, which we can see them securing at Bramall Lane on Saturday with a third straight clean sheet.
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