Accrington vs. Bristol Rovers (Saturday, 3.00pm)
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Relegation-threatened Accrington Stanley welcome Bristol Rovers to The City Ground in the latest round of League One matches this weekend.
John Coleman's side are currently languishing in the relegation zone, two points from safety, while The Pirates are firmly involved in the intensely-competitive playoff picture.
We say: Accrington Stanley 1-3 Bristol Rovers
On the back of only one league victory in their last 11 matches, we can predict playoff candidates Bristol Rovers moving closer to the top six with a hard-fought win over Accrington Stanley at The Crowd Ground on Saturday.
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Bolton vs. Portsmouth (Saturday, 3.00pm)
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Four days after Bolton Wanderers knocked Portsmouth out of the EFL Trophy, the two sides will resume battle when they go head-to-head in League One on Saturday.
The Trotters currently sit in the playoff places, while Pompey are 10 points worse off than their opponents, although they have played three games fewer than the Trotters.
We say: Bolton Wanderers 1-1 Portsmouth
While Bolton managed to get the better of Portsmouth on Tuesday, Pompey are unbeaten in their last four League One meetings against the Trotters, and we think that they will extend that run by holding their hosts to a draw on Saturday.
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Burton Albion vs. Shrewsbury (Saturday, 3.00pm)
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After the two sides were knocked out of the FA Cup last weekend, Burton Albion and Shrewsbury Town will turn their attention back to league action when they face off at the Pirelli Stadium on Saturday.
While the Brewers are currently sat in the League One relegation zone, Shrewsbury are seven points better off in 17th position.
We say: Burton Albion 1-2 Shrewsbury Town
Shrewsbury may have lost their last four matches, but they have won their previous two meetings with Burton, and we think the visitors will continue their impressive head-to-head record by claiming a narrow victory on Saturday.
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Cambridge vs. Morecambe (Saturday, 3.00pm)
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Two relegation-threatened sides that sit level on 24 points will face off in League One on Saturday when Cambridge United welcome Morecambe to the Abbey Stadium.
While the U's have lost their last three games, Morecambe will want to continue to build momentum as they look to claim a fourth consecutive victory.
We say: Cambridge United 0-2 Morecambe
Although Morecambe have lost their last five meetings against Cambridge, they enter Saturday's contest as the in-form side, and as a result, we think that they will continue their impressive run of form by claiming a fourth consecutive victory.
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Charlton vs. Barnsley (Saturday, 3.00pm)
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Playoff candidates meet on Saturday afternoon when Charlton Athletic entertain Barnsley at The Valley.
With only the top three teams in League One emerging victorious in more matches this season than Michael Duff's side, The Tykes have been in a determined mood for an immediate return to the Championship.
Meanwhile, The Addicks will need to replicate their visitors' current form to stand any chance of joining the South Yorkshire-based side in the second tier of English football next season.
We say: Charlton Athletic 2-3 Barnsley
With aspirations of taking full advantage of their current games in hand, we predict that Barnsley will edge out an end-to-end five-goal thriller at The Valley.
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Cheltenham vs. Derby (Saturday, 3.00pm)
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Derby County will be looking to make it four wins on the spin when they travel to the Completely-Suzuki Stadium to take on Cheltenham Town on Saturday afternoon.
The Rams are aiming to secure a return to the Championship at the first attempt, while the Robins have more modest ambitions and will look to put some more breathing room between themselves and the relegation zone.
We say: Cheltenham Town 0-1 Derby County
Derby County's away matches are almost exclusively low-scoring affairs, so this one should be no different, even considering the disparity between the teams in the league table.
Given the fact that Cheltenham have beaten some decent opponents at home this season, it will not be easy for the Rams, who we predict to win by a one-goal margin.
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Exeter vs. Forest Green (Saturday, 3.00pm)
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Exeter City have a great opportunity to make it three League One wins in a row when they take on Forest Green Rovers at St James Park on Saturday afternoon.
The home side are now up to 11th in the table after solid recent form, while the visitors will be unable to escape the relegation zone even with a victory, currently four points from safety at the bottom of the table.
We say: Exeter City 2-0 Forest Green Rovers
Forest Green Rovers are in desperate need of a win after their recent results, but they are coming up against Exeter at completely the wrong time, with the hosts likely to be full of confidence after their recent victories.
As such, we expect the Grecians to run out comprehensive 2-0 winners, extending their winning run to three games on the spin.
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Fleetwood vs. Oxford Utd (Saturday, 3.00pm)
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Fleetwood Town welcome Oxford United to the Highbury Stadium on Saturday afternoon.
Both sides head into the latest round of League One matches separated by only goal difference, hoping to take a step closer to the playoff positions rather than looking over their shoulders at the potential of dropping down towards the relegation zone.
We say: Fleetwood Town 1-1 Oxford United
After a close encounter between these two at the Kassam Stadium in November last year, in which they shared the spoils of the points, we forecast a similar outcome in Lancashire on Saturday.
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Ipswich vs. Plymouth (Saturday, 3.00pm)
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Ipswich Town host Plymouth Argyle in a top-of-the-table League One clash at Portman Road on Saturday afternoon.
The home side are in third place and could move into the top two with a victory, while the visitors are seven points clear of their opponents in first place.
We say: Ipswich Town 0-0 Plymouth Argyle
Plymouth drew their last League One away game 0-0 against fifth-placed Bolton Wanderers, and so a similar result should be expected on Saturday, with very little separating the two teams.
That result is likely to suit the visitors far more than the hosts, as it would maintain Argyle's seven-point lead over Ipswich, setting them up nicely for an easier game at home to Cheltenham next weekend.
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MK Dons vs. Lincoln (Saturday, 3.00pm)
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MK Dons will have the opportunity to move out of the League One relegation zone when they host Lincoln City at Stadium MK on Saturday afternoon.
The home side are currently 23rd, three points from safety, while the visitors are firmly rooted in mid-table, sitting in 16th place after 24 games played.
We say: MK Dons 2-3 Lincoln City
Lincoln City have the perfect opportunity to put an end to their bad run of form on Saturday, given MK Dons' struggles at home, and we expect them to win by a narrow margin.
Clean sheets have often eluded both teams in recent weeks, so there could well be plenty of goals, but the Imps just have that extra little bit of quality.
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Wycombe vs. Sheff Weds (Saturday, 3.00pm)
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On the back of their eye-catching FA Cup triumph over Newcastle United last weekend, Sheffield Wednesday will return to League One action with a trip to take on Wycombe Wanderers on Saturday.
The Owls were finally able to break into the top two of the League One table with a thrashing of Cambridge United at the beginning of the year, while their hosts sit seventh with just a two-point gap to the playoff places.
We say: Wycombe Wanderers 1-2 Sheffield Wednesday
Sheffield Wednesday feel like somewhat of an unstoppable force at present and will have even more confidence on the back of last weekend's performance and result at Hillsborough.
While Saturday will certainly be a tricky test away at one of the league's other form sides, we back the Owls to come through the challenge and return home with three more points.