Pontevedra vs. Getafe (Wednesday, 6.30pm)
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Pontevedra CF will be looking to produce another Copa del Rey upset when they welcome Getafe to Estadio Municipal de Pasaron for Wednesday's last-16 clash.
The fourth-tier hosts have already eliminated two La Liga sides, including Mallorca in the round of 32, while the Azulones squeezed past Granada in their recent cup tie.
We say: Pontevedra CF 1-2 Getafe
Pontevedra will be looking to pull off another upset in Wednesday's Copa del Rey tie, but while we think they could run Getafe close, we think that the visitors' top-flight quality will help them claim a narrow victory in the last-16 clash.
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Almeria vs. Leganes (Wednesday, 6.30pm)
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A place in the Copa del Rey quarter-finals will be at stake when second-tier Almeria play host to La Liga's Leganes on Wednesday.
The hosts pulled off an upset against Sevilla to seal their spot in the last 16, while the visitors dispatched Cartagena to continue their cup journey.
We say: Almeria 2-1 Leganes
Almeria may be competing in the league below Leganes, but in truth, there is little to choose between the two sides, with the hosts flying at the top of Segunda and the visitors currently battling to remain in La Liga.
Having won seven of their last eight home games, we believe that the Andalusian team will do enough to claim a narrow win to seal their place in the quarter-finals.
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Barcelona vs. Betis (Wednesday, 8.00pm)
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Buoyed by their Spanish Super Cup success, Barcelona will be looking to claim another victory when they play host to Real Betis in Wednesday's Copa del Rey clash.
The Blaugrana dispatched Barbastro to reach the last 16, while Betis saw off second-tier Huesca in their most recent Copa del Rey outing.
We say: Barcelona 3-1 Real Betis
Barcelona may have lost their final three home games of 2024, but they will head into Wednesday's cup fixture in a confident mood after winning their first three matches of 2025, including Sunday's Spanish Super Cup final, and we think that they will continue to build momentum by recording a relatively comfortable victory over Betis.
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Elche vs. Atletico (Wednesday, 8.30pm)
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La Liga leaders Atletico Madrid will travel to the Estadio Martinez Valero for Wednesday's Copa del Rey clash against second-tier Elche.
The hosts swept past Las Palmas in their last cup outing, while Atletico secured their place in the last 16 with a narrow win over Marbella.
We say: Elche 0-2 Atletico Madrid
The two sides will both enter Wednesday's fixture full of confidence thanks to their respective unbeaten runs, but we think that Atleti's La Liga quality will prove to be a decisive factor, which is why we believe that they will become the first team to beat Elche at the Estadio Martinez Valero since Huesca in August.