Tottenham Hotspur will be aiming to move 13 points clear of Liverpool in the Premier League by beating them on Sunday.
However, they will have to do so without star forward Son Heung-min - who scored in both league fixtures against Liverpool last weekend - after the South Korea forward suffered a fractured eye socket in their 2-1 win against Marseille in the Champions League in midweek.
The Reds, meanwhile, will view this as a hugely significant fixture as they will not want to fall so far behind the top three sides in the division by suffering a third successive league defeat.
Here, Sports Mole rounds up all of the latest team news for both sides ahead of Sunday's huge clash at the Tottenham Hotspur Stadium.
TOTTENHAM HOTSPUR vs. LIVERPOOL
© Reuters
TOTTENHAM HOTSPUR
Out: Son Heung-min (eye), Cristian Romero (muscle), Richarlison (calf)
Doubtful: Dejan Kulusevski (muscle)
Sports Mole's predicted XI: Lloris; Dier, Lenglet, Davies; Emerson, Bissouma, Bentancur, Hojbjerg, Perisic; Moura, Kane
LIVERPOOL
Out: Diogo Jota (calf), Luis Diaz (knee), Joel Matip (calf), Arthur Melo (muscle), Naby Keita (muscle), James Milner (concussion)
Doubtful: None
Sports Mole's predicted XI: Alisson; Alexander-Arnold, Konate, Van Dijk, Robertson; Henderson, Fabinho, Thiago; Salah, Firmino, Nunez
For data analysis of the most likely results, scorelines and more for this match please click here.