AZ vs. Heerenveen (Sunday, 11.15am)
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Unbeaten in their last three league games, ninth-placed Heerenveen travel to the AFAS Stadion to face off against AZ Alkmaar on Sunday.
The visitors have a chance to gain revenge for the 3-0 defeat that they suffered at the hands of their hosts when the sides met in November's reverse fixture.
We say: AZ Alkmaar 3-1 Heerenveen
Heerenveen are enjoying a mini purple patch at the moment, but we expect that to come to an end when they face an AZ side who recently got back to winning ways.
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Utrecht vs. VVV-Venlo (Sunday, 1.30pm)
VVV-Venlo travel to the Stadion Galgenwaard on Sunday for their clash against FC Utrecht, who have been on the rise in recent weeks.
Both teams have an identical record of three wins, a draw and a loss from the last five league games, so there is little to choose between them at the moment.
We say: FC Utrecht 2-1 VVV-Venlo
The teams are high on confidence going into this one, so it is hard to see either team running away with it. Notwithstanding, we expect Utrecht to narrowly take the victory in what should be an entertaining affair.
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Feyenoord vs. Willem II (Sunday, 1.30pm)
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Two sides who have recently had a two-week resting period due to their postponed fixtures last time out square up in Willem II's visit to Feyenoord on Sunday.
With huge ramifications at both ends of the Eredivisie table, the game at De Kuip is a crucial one for either side albeit for very different reasons.
We say: Feyenoord 3-0 Willem II
Willem II have neither the defensive solidity to prevent their hosts from scoring, nor the attacking impetus to cause problems of their own, so an easy victory for Feyenoord is expected in this one.
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Vitesse vs. FC Twente (Sunday, 3.45pm)
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Vitesse and FC Twente draw the curtain on gameweek 22 of the Eredivisie season with their meeting at the GelreDome on Sunday.
Both teams are without a win in their last three league games apiece, and a victory here would be a very welcome one for either side.
We say: Vitesse 2-1 FC Twente
Twente are on a bad run of form at the moment, and we expect their woes to be compounded at Vitesse, who should be able to secure all three points in this one.