Chelsea vs. Bayern Munich (Tuesday, 8pm)
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Chelsea head into the first leg of their Champions League last-16 tie with Bayern Munich on the back of a morale-boosting win over Tottenham Hotspur.
Meanwhile, the German outfit make the trip to Stamford Bridge having maintained top spot in the Bundesliga with a hard-fought triumph against Paderborn.
We say: Chelsea 1-3 Bayern Munich
Although Chelsea are on a high after the success over Spurs, this represents a tougher challenge for the Blues. While Bayern had issues at the back on Friday, we feel that they will have too much quality for their hosts at the other end of the pitch.
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> How Chelsea could line up against Bayern Munich
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Napoli vs. Barcelona (Tuesday, 8pm)
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Barcelona make the trip to Italy to face Napoli in the first leg of their Champions League last-16 tie having put together a three-match winning streak in La Liga.
The home side have also enjoyed a strong recent run, registering three victories in all competitions to boost their chances in Serie A and the Coppa Italia.
We say: Napoli 1-2 Barcelona
Given Napoli's recent form, Barcelona should not have it all their own way on Tuesday evening. However, the visitors are starting to improve under Setien, and we feel that the Catalan outfit will return to Spain with a slender advantage.
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> How Barcelona could line up against Napoli
> Click here for Barcelona's latest injury and suspension news ahead of this contest