Luis Enrique has handed a starting spot to Arda Turan up top in place of the suspended Neymar, as Barcelona take on Osasuna in La Liga.
The Brazilian ace picked up his fifth yellow card of the season in the 1-1 draw with Real Madrid last time out - a result that leaves the Catalan giants six points off their opponents.
Enrique was able to rest a number of players for the visit of Borussia Monchengladbach in the Champions League in midweek, but Javier Mascherano - one of three to keep his place in the XI for that 4-0 win - drops out this afternoon.
Samuel Umtiti will instead partner Gerard Pique in the heart of defence, with Sergi Roberto again preferred at right-back and Jordi Alba retaining his place on the opposite flank from the draw with Madrid.
Osasuna, who will be looking to prolong Barcelona's month-long wait for a league win, are still without Didier Digard who is a long-term absentees, but Javier Flano is back for the first time since August.
Los Rojillos are bottom of the table with just one win all season, sitting five points from safety ahead of this visit from the reigning Spanish champions at El Sadar.
Osasuna: Nauzet; Oier, Flano Marquez, Clerc; Causic, Torres, De las Cuevas, Berenguer; Leon, Riera
Barcelona: Ter Stegen; S.Roberto, Pique, Umtiti, Alba; Busquets, Gomes, Iniesta; Messi, Suarez, Turan
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