Tottenham Hotspur manager Antonio Conte has revealed that Sergio Reguilon could be sidelined for the remainder of the season ahead of Saturday's trip to face quadruple-chasing Liverpool.
Spurs visit Anfield in a huge match for both the title race and the battle for Champions League football next season, with the visitors currently two points adrift of fourth-placed North London rivals Arsenal, whom they face next week.
Reguilon's potentially season-ending groin injury deepens a shortage of players in the squad, with Conte claiming to only have 15 fit senior players for the trip up to Merseyside.
Spurs are especially lacking in the full-back areas, with Matt Doherty and Japhet Tanganga joining Reguilon on the sidelines for the rest of the season.
Oliver Skipp will also not feature again this term, but Tottenham do not have any new injury concerns following the 3-1 win over Leicester City last time out.
Danger men Harry Kane and Son Heung-min got the goals in that game, with Son bearing down on Liverpool's Mohamed Salah in the Golden Boot race - now with 19 to his name this season.
Kane, meanwhile, will be looking to extend a good run against Liverpool which has seen him directly contribute to nine goals in 13 Premier League meetings, including scoring four times and assisting once in seven outings at Anfield.
Both Son and Kane will hope to capitalise on Liverpool's high defensive line, and Dejan Kulusevski is expected to return to that front three in place of Lucas Moura, having sat out against Leicester.
Conte's limited options mean that that could be the only change made by the Italian, who named youngsters Harvey White, Dane Scarlett and Matthew Craig on the bench last time out.
Tottenham Hotspur possible starting lineup: Lloris; Romero, Dier, Davies; Emerson, Bentancur, Hojbjerg, Sessegnon; Kulusevski, Kane, Son
> Click here to see how Liverpool could line up for this fixture
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