Manchester United goalkeeper David de Gea will start between the posts for Spain in their Under-21 European Championship opener against Russia.
The 22-year-old will play his first game since clinching the Premier League title with the Red Devils, while former Bolton Wanderers loanee striker Rodrigo starts in attack.
Isco, who has been widely tipped to join Manchester City this summer from Malaga, has been given the nod to start, while Iker Muniain starts up front.
For Russia, Dynamo Moscow striker Andrei Panyukov has failed to make the starting lineup after suffering a knock in training, but the forward has been placed on the bench.
Spain XI: De Gea; Montoya, Bartra, Inigo, Martinez; Moreno, Illarramendi, Thiago Alcantara, Isco; Rodrigo, Tello, Muniain
Subs: Marino, Joel, Nacho, Marc Muniesa, Alvaro, Carvajal, Canales, Koke, Camacho, Sarabia, Morata, Alvaro Vazquez
Russia XI: Zabolotni; Schennikov, Chicherin, Burlak, Belyaev; Tsallagov, Petrov, Shatov, Bibilov; Yakovlev, Cheryshev
Subs: Kritsuk, Filtsov, Bryzgalov, Kirillov, Emelyanov, Grigoryev, Zotov, Panyukov, Kanunnikov