Venezia vs. Sampdoria (Sunday, 11.30am)
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A crucial encounter at the bottom of Serie A takes place on Sunday, when 16th-placed Sampdoria travel to face Venezia, who currently sit four points behind their opponents in 18th spot.
Venezia have a game in hand to their advantage on the three teams above them, but both of these sides will be looking to return to winning ways after three consecutive defeats.
We say: Venezia 1-2 Sampdoria
This encounter is likely to be a close affair with a lot at stake in the race to beat relegation, but having shown some more attacking prowess than their hosts this season, Sampdoria should come out on top.
Both teams are in poor form, which could suggest that there will be goals on Sunday for both sides, with neither Venezia or Sampdoria used to keeping clean sheets.
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Empoli vs. Hellas Verona (Sunday, 2.00pm)
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Still searching for their first Serie A success of 2022, Empoli welcome mid-table rivals Hellas Verona to Stadio Carlo Castellani on Sunday.
After losses for both clubs last week, they convene in Tuscany with the home side having both drawn and lost six of their last 12 league outings.
We say: Empoli 2-1 Hellas Verona
Empoli have conceded 11 times in the opening 15 minutes of play in Serie A this season - the joint-most of any team (level with rock-bottom Salernitana) - while no side has scored more in this period than Verona's 11.
Therefore, the opening stages could prove crucial to the overall outcome, and if the hosts survive unscathed, their winless run can come to an end against a depleted visiting side.
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Juventus vs. Salernitana (Sunday, 2.00pm)
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Just days after their Champions League implosion, Juventus aim to pick up the pieces of their season against Serie A's rock-bottom side Salernitana on Sunday.
Heavily beaten by Villarreal on Wednesday, Juve are now hoping to haul themselves back into the Scudetto race, and face an away side in search of a miracle to survive having been unable to turn draws into wins.
We say: Juventus 2-0 Salernitana
Their midweek aberration aside, Juve have been an efficient machine in recent months, though rarely registering high on the spectacular scale.
Another regulation dispatch is in the cards against a porous Salernitana, who are fast running out of time to make the greatest of great escapes.
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Roma vs. Lazio (Sunday, 5.00pm)
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Eternal City rivals Roma and Lazio clash at Stadio Olimpico on Sunday evening, and the Derby della Capitale takes centre stage as Serie A heads towards its fascinating finale.
With the two foes divided by just a point and two places in the standings, not only capital city supremacy is at stake, but also a potential place in Europe.
We say: Roma 1-2 Lazio
Having given the impression they are running on fumes - relying on yet another late goal as recently as Thursday night, and only scoring once in each of their last five games - Roma's momentum could be halted this weekend.
If Immobile - fuelled by his battle with Dusan Vlahovic to be crowned Serie A's top scorer - can deliver the goods when it most matters, then Lazio can take advantage; pulling clear of their Olimpico co-tenants in the table.
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Bologna vs. Atalanta (Sunday, 7.45pm)
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In sharp contrast to their domestic form, Atalanta BC won again in Europe this week, so now seek to get their Serie A campaign back on track with victory over Bologna on Sunday.
Despite four successive continental wins taking them into the Europa League quarter-finals, the Bergamaschi have slid to sixth in the league standings following a goalless draw with Genoa last week, while their hosts continue to toil in mid-table mediocrity.
We say: Bologna 0-1 Atalanta BC
Both Atalanta and Bologna have failed to score in five Serie A games so far in 2022 - only relegation candidates Genoa have fared worse in that regard - and the visitors could be suffering from a European hangover too.
Therefore, a tightly-contested game may have to be decided by a moment of magic from La Dea's underperforming cast of attacking stars.