We say: Manchester United 2-1 Leicester City
As emphatic as Man United's success over Leicester was in the EFL Cup, the Van Nistelrooy bounce has maybe worn off slightly since then, and the Foxes will likely set up to frustrate their hosts this weekend.
Cooper's men have lacked defensive nous on the road all season long, though, so Van Nistelrooy should go out on a high before passing the reins over to Amorim.
Read more.Data Analysis
Our analysis of all available data, including recent performances and player stats, suggests the most likely outcome of this match is a Manchester United win with a probability of 55.69%. A win for Leicester City has a probability of 23.35% and a draw has a probability of 21%.
The most likely scoreline for a Manchester United win is 2-1 with a probability of 9.57%. The next most likely scorelines for that outcome are 2-0 (7.37%) and 1-0 (7.05%). The likeliest Leicester City win is 1-2 (5.94%), while for a drawn scoreline it is 1-1 (9.15%).