Spezia vs. Salernitana (Saturday, 2.00pm)
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Two of the bottom three in Serie A meet on Saturday afternoon, as Spezia welcome Salernitana to Stadio Alberto Picco.
Both just a point off the foot of the table having won only one game apiece, the two modest clubs convene for the first time ever in the top-flight, searching for success against a likely relegation rival.
We say: Spezia 2-1 Salernitana
Spezia can halt their worrying losing streak at the Picco with a close-fought win over one of their close rivals for Serie A salvation.
Potentially facing visitors shorn of several regular starters through injury, the Aquilotti are set to pick Salernitana off and consequently leapfrog them in the table.
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Lazio vs. Inter Milan (Saturday, 5.00pm)
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Two weeks after extending their unbeaten Serie A record to seven games, Inter Milan visit Stadio Olimpico, where they meet an inconsistent Lazio side.
While the champions - under ex-Biancocelesti coach Simone Inzaghi - won at Sassuolo last time out to sit third in the table, their hosts were surprisingly beaten by Bologna; continuing their hit-and-miss start to the campaign.
We say: Lazio 1-1 Inter Milan
Though Lazio's defensive deficiencies have undermined their consistency this term - and Inter are seemingly able to score at will - the home side always take inspiration from performing at the Olimpico, and can therefore share the spoils on Saturday.
The champions are likely to be frustrated in their efforts to claw back ground on the two teams above them, ahead of a big week in which they face both Sheriff and Juventus back home in Milan.
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AC Milan vs. Hellas Verona (Saturday, 7.45pm)
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Seeking to sustain their superb domestic form, unbeaten AC Milan return to Serie A duty on Saturday evening, versus Hellas Verona at San Siro.
While the Rossoneri have experienced troubles in Europe, they have so far excelled in the Italian top flight, and now meet visitors who have markedly improved under new management - scoring 12 times in their last four games.
We say: AC Milan 2-1 Hellas Verona
Milan may be decimated by injuries, but their squad has gained an encouraging depth over recent transfer windows, and can endure the absence of integral cogs in their well-oiled machine.
A confident and mobile forward line should prove too hot to handle for the vulnerable Verona defence, as the likes of Leao and Diaz continue to lead the transition from one Rossonero generation to the next.