We say: PSV Eindhoven 1-2 Monaco (Monaco win 3-2 on aggregate)
Both managers could afford to rest key names at the weekend, but both must also work around a number of injury concerns for the second leg, which should prove to be another tense and closely-fought affair.
The returns of Golovin and Volland with fresh legs in tow could just tip the balance in Monaco's favour, especially as Clement's side have not shied away from a shot so far this season, and victory should be theirs if they can bury said chances at the Phillips Stadion.
Read more.Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Monaco win with a probability of 39.91%. A win for PSV Eindhoven had a probability of 37.59% and a draw had a probability of 22.5%.
The most likely scoreline for a Monaco win was 1-2 with a probability of 8.29%. The next most likely scorelines for that outcome were 0-1 (5.61%) and 0-2 (4.9%). The likeliest PSV Eindhoven win was 2-1 (8.02%), while for a drawn scoreline it was 1-1 (9.49%). The actual scoreline of 3-2 was predicted with a 4% likelihood.