Carlisle vs. Barrow (Saturday, 1.00pm)
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Fifth hosts fourth in an eye-catching League Two battle on Saturday afternoon, as Carlisle United meet fellow promotion hopefuls Barrow.
Paul Simpson's side played out a 1-1 draw with Sutton United in their most recent battle, while the visitors' patchy spell continued as they were thumped 5-0 by Stevenage.
We say: Carlisle United 1-1 Barrow
A cagey affair could be in store between two sides separated by just one point in the standings, and neither crop of players have covered themselves in glory recently.
Barrow should give themselves a fighting chance of avoiding yet another defeat on the road if they can cut out the individual errors, but Carlisle may have to accept another point on their own territory.
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Crewe vs. Leyton Orient (Saturday, 1.00pm)
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Leyton Orient will look to extend their lead at the top of the League Two table when they travel to the Mornflake Stadium to take on Crewe Alexandra this Saturday.
After being relegated from League One last season, the Railwaymen are in less impressive form and will commence proceedings 15th in the standings, although they have a game in hand on the majority of the teams in the division.
We say: Crewe Alexandra 0-2 Leyton Orient
Given the fact that Crewe lost their last home match, it is likely that they will come unstuck once again against the league leaders. Although the O's lost here in November, they have won their last three league games and are in inspired form, so they should be able to cement their place at the top of League Two in comfortable fashion.
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Harrogate vs. Northampton (Saturday, 1.00pm)
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Northampton Town will be looking to further prove their title credentials when they visit Harrogate Town's Wetherby Road this weekend.
Harrogate find themselves in 20th place after a horrendous start to the season and, though their form has picked up in the last six weeks, they hover precariously over the relegation places. Meanwhile, the visitors sit in third place, and will go into their away game confident of picking up all three points.
We say: Harrogate Town 2-2 Northampton Town
Nobody will argue against the fact that Northampton come into the game stronger on paper; their league form more than supports such an idea, and the consistency and confidence of Brady's coaching has given much hope to the Cobblers' dreams of promotion.
However, coming up against an inspired Harrogate team bountiful with goals in recent weeks may prove a challenge too difficult to overcome away from home.
An even, competitive match full of risk-taking and high-pace counter-attacks will see a score draw at Wetherby Road this weekend, and expect goals from the in-form Luke Armstrong and Sam Hoskins.
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Grimsby Town vs. Tranmere (Saturday, 3.00pm)
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Grimsby Town will be looking to secure a first home league win since October when they take on Tranmere Rovers at Blundell Park in League Two on Saturday afternoon.
The Mariners are currently 16th in the standings and able to overtake their opponents in the table if they win the match, with the visitors starting proceedings three points higher.
We say: Grimsby Town 0-0 Tranmere Rovers
Both sides are in poor form at the moment, with Grimsby particularly struggling to win home matches, so the likely outcome is a draw. In light of Tranmere struggling in front of goal, and the Mariners not scoring in two of their last three games, a stalemate is a real possibility.
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Newport vs. Doncaster (Saturday, 3.00pm)
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Newport County face Doncaster Rovers at Rodney Parade on Saturday in pursuit of a hat-trick of league victories in a row.
Separated by only six points, the Exiles could move further away from the relegation zone with a win depending on other results. Meanwhile, three points could move Doncaster into the top half of the table.
We say: Newport County 1-1 Doncaster Rovers
In pursuit of their first victory in three matches, Doncaster Rovers will again look to top scorer George Miller if they are to get anything from a tricky expedition to Newport County.
However, a share of the spoils could be the most likely outcome, with both sides currently hovering within the mid-table mediocrity of League Two.
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Salford City vs. Walsall (Saturday, 3.00pm)
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Salford City face Walsall at the Peninsula Stadium on Saturday, with both sides narrowly outside the playoff positions.
Walsall are unbeaten in eight matches across all competitions, dating back to the middle of October, while Salford have been victorious in three of the last four head-to-head encounters.
We say: Salford City 1-2 Walsall
Hoping to avenge their 2-1 defeat against Salford City last season, Walsall should have enough firepower in the final third to register another victory.
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Swindon vs. AFC Wimbledon (Saturday, 3.00pm)
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Seeking to move into the promotion playoff places, Swindon Town play host to AFC Wimbledon at the County Ground Stadium in round 21 of the League Two on Saturday.
Having completed an impressive league double over the home side last season, Johnnie Jackson's side will be looking to continue in the same vein and pick up a third league win on the trot.
We say: Swindon Town 0-2 AFC Wimbledon
With just two points separating Swindon Town and AFC Wimbledon in the standings, we anticipate an end-to-end affair with both sides going all out for the victory. However, the Dons are favourites heading into the weekend as the home side have suffered a slump in form and struggled to find the back of the net in recent weeks.
