Brighton & Hove Albion and Tottenham Hotspur will both be aiming to bounce back from respective defeats in Wednesday's Premier League encounter at the Amex Stadium.
The Seagulls were on the wrong end of a 2-0 scoreline against Liverpool last time out, while Antonio Conte's side were sunk 3-2 by top-four rivals Manchester United.
Match preview
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Robert Sanchez may have inexplicably escaped punishment for his high challenge on Luis Diaz during Saturday's early kickoff, but the Brighton goalkeeper could only watch the ball trickle into the back of the net as his unorthodox attempts to stop the Liverpool attacker failed to bear fruit.
Mohamed Salah made sure of the result for Liverpool from the spot after Yves Bissouma's handball in the 61st minute as Brighton's dreadful run of form continued, with Graham Potter's side now looking down the table rather than towards the top half.
The Seagulls' solid start to the campaign has been consigned to history as they occupy 13th spot in the rankings - still just three points off a potential place in the top 10 - and there should not be any demotion fears around the Amex with Brighton 11 clear of the drop zone.
A run of five successive defeats can arguably be viewed as relegation form - with Brighton only finding the back of the net once and conceding at least twice in every game during that miserable period - and Potter's draw specialists have certainly lost their resilient streak.
The Seagulls have also now lost their last three on the bounce at home without scoring following the loss to Liverpool and have only prevailed in one of their last 11 Premier League games at the Amex, so the stage is set for Antonio Conte's side to bounce back.
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The mouthwatering centre-forward showdown between Harry Kane and Cristiano Ronaldo at Old Trafford had one clear winner on Saturday evening, as Man United's timeless veteran silenced the critics and proved that he was only a problem for the opposition rather than his own club.
Twice Ronaldo gave Man United the lead - the 37-year-old's opener was truly a thing of beauty - and twice they were pegged back by Kane's penalty and a Harry Maguire own goal, but Ronaldo rose highest in the 81st minute to complete his hat-trick and boost the Red Devils' top-four hopes at the expense of Tottenham's.
The streak of inconsistency under Conte does not look like ending anytime soon for Tottenham, who enter the midweek round of fixtures now outside of the European spots in eighth place and six points behind fourth-placed Arsenal having played a game more.
Spurs' games in hand on Wolverhampton Wanderers, West Ham United and Man United must be taken into account, but Conte has now overseen four defeats from his last six away from home in all competitions, while the North London club are also still awaiting their first draw of 2022.
Tottenham eased to a 3-1 win over the Seagulls in the FA Cup just last month, but Brighton have won the last two Premier League meetings between the sides at the Amex Stadium without conceding and may fancy their chances against this hit-and-miss Lilywhites outfit here.
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Team News
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Brighton midfielder Adam Lallana lasted just eight minutes against his former club as a substitute before coming off with a suspected hamstring issue, and while Potter believes the issue is only a minor one, he will miss out here.
Potter also confirmed at his press conference that Adam Webster would not be fit for Wednesday, with the fixture against Norwich City after the international break a more realistic target.
Jakub Moder, Pascal Gross and the fit-again Enock Mwepu are all ready to freshen up the Seagulls' midfield, while Shane Duffy could return to the backline if Potter feels the need to adopt a more defensive approach.
As for Tottenham, Oliver Skipp (groin) and Japhet Tanganga (knee) do not seem to be coming back anytime soon, while Ryan Sessegnon's muscular issue will likely keep him out until after the international break.
Conte did not pick up any fresh concerns at Old Trafford and is unlikely to consider many changes despite the defeat, with Sergio Reguilon deputising for Sessegnon on the left.
Tired legs could see Emerson Royal, Lucas Moura and Steven Bergwijn handed opportunities to impress from the start, but Dejan Kulusevski was one of the bright sparks on Saturday and will not want to lose his place.
Brighton & Hove Albion possible starting lineup:
Sanchez; Lamptey, Veltman, Dunk, Cucurella; Bissouma, Moder; March, Gross, Trossard; Maupay
Tottenham Hotspur possible starting lineup:
Lloris; Romero, Dier, Davies; Doherty, Hojbjerg, Bentancur, Reguilon; Kulusevski, Kane, Son
We say: Brighton & Hove Albion 1-3 Tottenham Hotspur
Despite their win-loss-win-loss routine under Conte in recent weeks, Spurs have never needed any lessons on finding the back of the net, which does not bode well for an out-of-sorts Brighton and their leaky defence.
The Seagulls have become a bit of a bogey team for Spurs on the road in recent years, but after claiming a 3-1 win in the cup last month, we can see lightning striking twice as Conte's side reignite their Champions League charge.
Top tip
Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Tottenham Hotspur win with a probability of 40.57%. A win for Brighton & Hove Albion had a probability of 32.9% and a draw had a probability of 26.5%.
The most likely scoreline for a Tottenham Hotspur win was 0-1 with a probability of 10.53%. The next most likely scorelines for that outcome were 1-2 (8.59%) and 0-2 (7.17%). The likeliest Brighton & Hove Albion win was 1-0 (9.27%), while for a drawn scoreline it was 1-1 (12.61%). The actual scoreline of 0-2 was predicted with a 7.2% likelihood. Our team at Sports Mole and our data analysis both correctly predicted that Tottenham Hotspur would win this match.