Tottenham Hotspur will endeavour to avoid a fourth successive defeat away from home when they travel to face Wolverhampton Wanderers in Saturday's Premier League battle.

Cristian Stellini oversaw a disappointing 1-0 defeat to Sheffield United in the FA Cup fifth round on Wednesday evening, with Iliman Ndiaye scoring the only goal of the contest in the second half.

Seeking an immediate response to missing out on another shot at silverware, Tottenham enter this weekend's fixtures sitting pretty in fourth in the Premier League table, having seen off Chelsea 2-0 last weekend.

Here, Sports Mole rounds up Tottenham's latest injury and suspension news ahead of the clash with Julen Lopetegui's side, who lost 2-0 to Liverpool on Wednesday.

Rodrigo Bentancur

Tottenham Hotspur's Rodrigo Bentancur walks off the pitch after sustaining an injury on February 11, 2023 © Reuters

Status: Out
Type of injury: Knee
Possible return date: Unknown

Tottenham will be without Rodrigo Bentancur for the rest of the season due to the ruptured ACL he suffered against Leicester City on February 11, and in the best case scenario, he could return at some point in September.

Hugo Lloris

Hugo Lloris in action for Tottenham Hotspur on October 1, 2022 © Reuters

Status: Out
Type of injury: Knee
Possible return date: April 1 (vs. Everton)

Hugo Lloris damaged knee ligaments in Spurs' win over Manchester City last month, and the captain is unlikely to take to the field again before next month.

Ryan Sessegnon

Ryan Sessegnon celebrates scoring for Tottenham Hotspur on August 6, 2022 © Reuters

Status: Out
Type of injury: Hamstring
Possible return date: April 1 (vs. Everton)

The injury-plagued Ryan Sessegnon is currently dealing with a fresh hamstring problem, and the ex-Fulham starlet will likely spend another few weeks on the treatment table too.

Yves Bissouma

Tottenham Hotspur's Yves Bissouma pictured in August 2022 © Reuters

Status: Out
Type of injury: Ankle
Possible return date: Unknown

Yves Bissouma recently went under the knife to address a stress fracture in his ankle, and no timeframe has been placed on the Mali international's recovery, but he will be missing for a number of weeks.

Emerson Royal

Status: Minor doubt
Type of injury: Knee
Possible return date: March 4 (vs. Wolves)

Emerson Royal was absent from Spurs' FA Cup loss to Sheffield United due to a knock to the knee, but he is expected to shake off the issue in time for Saturday's game.