Manchester United manager Jose Mourinho has handed starts to Henrikh Mkhitaryan and Jesse Lingard, while Manchester City goalkeeper Claudio Bravo will make his debut in this afternoon's derby at Old Trafford.
Mkhitaryan, who joined the Red Devils from Borussia Dortmund in the summer transfer window, will make his first Premier League start since joining the club.
Both the Armenian player and Lingard have recovered from injuries to take part in the clash, while Juan Mata and Anthony Martial have dropped to the bench as a result.
City boss Pep Guardiola has switched his full-backs for today's encounter as Bacary Sagna and Aleksandar Kolarov are preferred to Gael Clichy and Pablo Zabaleta.
Bravo, who recently signed from Barcelona, takes Wilfredo Caballero's place in goal, while Kelechi Iheanacho will lead the line up front, replacing banned Sergio Aguero.
Manchester United: De Gea; Valencia, Bailly, Blind, Shaw; Fellaini, Pogba; Mkhitaryan, Rooney, Lingard; Ibrahimovic
Subs: Romero, Smalling, Herrera, Mata, Schneiderlin, Martial, Rashford
Manchester City: Bravo; Sagna, Otamendi, Stones, Kolarov; Fernandinho, De Bruyne, Silva; Sterling, Nolito, Iheanacho
Subs: Caballero, Fernando, Sane, Zabaleta, Clichy, Navas, A. Garcia
Follow Sports Mole's live text commentary of the match here.
Danielle Joynson
