Wolves vs. Spurs (Saturday, 12.30pm)
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Having lost their Premier League unbeaten record in spectacular circumstances, Tottenham Hotspur endeavour to enter the international break on a high when they take on Wolverhampton Wanderers at Molineux in Saturday's lunchtime kickoff.
Ange Postecoglou's nine men were thumped 4-1 by London rivals Chelsea on Monday evening, while their hosts were left to rue another contentious VAR call in a 2-1 loss to Sheffield United.
We say: Wolverhampton Wanderers 2-2 Tottenham Hotspur
While some applauded Tottenham and Postecoglou for risking it all against Chelsea with a high defensive line, others lambasted the Australian as Jackson tapped in three times in the final 20 minutes, but one can be sure that the Spurs boss will continue with such tactics no matter what personnel is at his disposal.
Even with nine men, Tottenham were not without their opportunities on Monday, and given Wolves' recent propensity for both scoring and shipping goals, we can envisage an entertaining draw being played out on Saturday lunchtime.
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> How Tottenham could line up against Wolves
> Tottenham injury, suspension list vs. Wolves
Arsenal vs. Burnley (Saturday, 3.00pm)
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A Manchester City reunion will take place at the Emirates Stadium on Saturday, as Mikel Arteta's Arsenal take on Vincent Kompany's Burnley in the Premier League.
Both sides are seeking redemption for respective losses last weekend, as the Gunners' unbeaten streak came to an end at Newcastle United, while the Clarets set an unwanted record in a 2-0 reverse against Crystal Palace.
We say: Arsenal 2-0 Burnley
Teams that try to attack Arsenal often fare worse than teams who sit back and absorb Gunners pressure throughout the 90 minutes, and it will be fascinating to see if Kompany is willing to compromise his principles in the hope of holding out for a point.
Midweek fatigue and fresh knocks will also work against the Gunners, who have enjoyed little success in this fixture over the past few years, but Arteta's men ought to find their way through a leaky Burnley defence eventually as they enter the international hiatus on a high.
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> How Arsenal could line up against Burnley
> Arsenal injury, suspension list vs. Burnley
Crystal Palace vs. Everton (Saturday, 3.00pm)
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Having been denied victory in gut-wrenching circumstances last time out, Everton head south to take on Crystal Palace at Selhurst Park in Saturday's Premier League battle.
The Toffees were forced to settle for a point in a 1-1 draw with Brighton & Hove Albion in gameweek 11, while the hosts piled more misery on Burnley in a 2-0 beating.
We say: Crystal Palace 0-0 Everton
While Palace can proudly claim to be one of the three stingiest defences in the Premier League so far this season, Everton have failed to make the net score in five top-flight matches, more than any other team in the division.
As a result, it would be typical of the footballing gods to bless the Selhurst Park crowd with a glut of goals, but a low-scoring draw - potentially even a scoreless one - is the only outcome we can picture.
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Man Utd vs. Luton (Saturday, 3.00pm)
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Fresh from their chaotic Champions League implosion in midweek, Manchester United will attempt to return to winning ways when they welcome Luton Town to Old Trafford for a Premier League clash on Saturday.
While the under-pressure Red Devils currently sit eighth in the table, six points behind the top four, the Hatters are down in 17th place and are hovering just above the relegation zone on goal difference.
We say: Manchester United 3-1 Luton Town
Luton's valiant efforts against Liverpool have provided the Hatters fanbase with optimism that they can compete with the big boys this term, and they should not be taken lightly by an out-of-sorts Man United outfit on Saturday.
Anything other than a victory for Man United could increase speculation over Ten Hag's future, and although the Red Devils look vulnerable at the back, we believe that the hosts will find a way to come out on top and head into the international break on a much-needed high.
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> How Man United could line up against Luton
> Man United injury, suspension list vs. Luton
Bournemouth vs. Newcastle (Saturday, 5.30pm)
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Another Vitality Stadium homecoming awaits Eddie Howe on Saturday, as Newcastle United make the long trip south to take on Bournemouth in the Premier League's evening kickoff.
Both sides are aiming to bounce back from demoralising losses, as the Cherries were crushed 6-1 by Manchester City last time out, while the Magpies went down 2-0 to Borussia Dortmund in the Champions League.
We say: Bournemouth 0-1 Newcastle United
Bournemouth could hardly be facing a decimated Newcastle squad at a more ideal time, but the Cherries' perennial defensive woes still makes it difficult to envisage Iraola's side claiming a shock result at the Vitality.
Howe's squad is stretched incredibly thin right now, but Bournemouth are hardly in tip-top shape either, and as was the case against Arsenal, the Magpies can strike first and hold what they have to prolong their unbeaten run in the Premier League.