Marcus Rashford and Luke Shaw are back in the Manchester United starting side for Sunday's FA Cup semi-final with Brighton & Hove Albion at Wembley.
The duo made their injury returns as second-half substitutes in the 3-0 loss to Sevilla on Thursday night.
Rashford takes Jadon Sancho's position on the left of the attack, while Shaw comes in for the suspended Harry Maguire, with the left-back operating in the middle of the defence alongside Victor Lindelof.
There is also a return to the side for Bruno Fernandes, who was suspended for the second leg of the Europa League quarter-final against Sevilla.
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Fernandes comes in for Marcel Sabitzer, who has dropped to a bench which also includes the likes of Fred, Wout Weghorst and Tyrell Malacia.
Anthony Martial limped off against Sevilla, fuelling suggestions that the Frenchman could be set for another spell on the sidelines, but he has been cleared to lead the attack.
There are no real surprises considering the players that are unavailable to Erik ten Hag, with Lisandro Martinez, Raphael Varane, Scott McTominay and Alejandro Garnacho among those out.
Ten Hag will be demanding a response from his players following the disappointment of the Europa League exit to Sevilla, with goalkeeper David de Gea heavily criticised for his performance.
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As for Brighton, their side shows two changes from the one that took to the field against Chelsea in the Premier League last weekend.
Joel Veltman drops out of the side, with Pascal Gross set to start at right-back, while Julio Enciso and Danny Welbeck are the players to come in, as Evan Ferguson is out with an ankle injury.
Welbeck will lead the line against his former club, with Solly March, Enciso and Kaoru Mitoma providing the support from a deeper position.
There are again starts in midfield for Moises Caicedo and Alexis Mac Allister, who continue to be heavily linked with big-money moves away from the Seagulls this summer.
Brighton & Hove Albion: Sanchez; Gross, Webster, Dunk, Estupinan; Caicedo, Mac Allister; March, Enciso, Mitoma; Welbeck
Subs: Steele, Colwill, Undav, Ayari, Gilmour, Van Hecke, Veltman, Offiah, Buonanotte
Manchester United: De Gea; Wan-Bissaka, Lindelof, Shaw, Dalot; Fernandes, Casemiro, Eriksen; Antony, Martial, Rashford
Subs: Butland, Malacia, Sabitzer, Fred, Sancho, Weghorst, Pellistri, Williams, Elanga