Lyon have booked their place in the last 32 of the Coupe de France with a 3-2 victory over Lens this afternoon.
Nabil Fekir, Alexandre Lacazette and Mouhamadou Dabo all struck inside the opening 30 minutes, and the five-time winners held on to win despite late goals from Alharbi El Jadeyaoui and Adamo Coulibaly.
Cup holders Guingamp have kept alive their hopes of defending the trophy with a 3-0 win over fifth-division outfit Dinan-Lehon, thanks to a double from Claudio Beauvue and an effort from Jeremy Pied.
Monaco, who last won the competition in 2008, needed goals from Bernardo Silva and Valere Germain to ensure a 2-0 win over Ligue 2 side Nimes.
Bordeaux, winners in 2013, put aside their recent dip in form in the league to beat Toulouse 2-1.
Thomas Toure and Emiliano Sala gave Les Girondins a two-goal lead, although Wissam Ben Yedder's penalty ensured a nervy finish.
An extra-time winner from Franck Tabanou confirmed Saint-Etienne's passage to the next stage as they eventually saw off Nancy by earning a 1-0 victory.
Results in full: Bordeaux 2-1 Toulouse, Dinan-Lehon 0-3 Guingamp, Lens 2-3 Lyon, Nimes 0-2 Monaco, Saint Etienne 1-0 Nancy AET