Sassuolo vs. Cagliari (Sunday, 11.30am)
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Running out of time to save their Serie A status, Sassuolo face a crucial six-pointer on Sunday, when they host relegation rivals Cagliari.
Both sides lost last week, leaving the Neroverdi three points adrift of safety and their Sardinian counterparts only one above the drop zone.
We say: Sassuolo 2-2 Cagliari
Sassuolo and Cagliari have drawn 10 of their 17 Serie A meetings to date, and the same result may be produced this weekend; the hosts cannot keep a lead intact, while their visitors struggle outside of Sardinia.
That would leave both at the mercy of other teams in a tense survival scrap that is set to climax on the last day of the season.
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Monza vs. Frosinone (Sunday, 2.00pm)
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Monza risk going eight Serie A games without winning when they host relegation-threatened Frosinone at the U-Power Stadium in Sunday's gameweek 37 fixture.
The Biancorossi's underwhelming end to year two in the top division gives the Canaries hope of a much-needed victory, with the struggling side ahead of 18th-placed Empoli on head-to-head points.
We say: Monza 1-1 Frosinone
Excluding the hammering at the hands of Inter, Frosinone have typically been hard to beat since the March hiatus. However, wins have been hard to come by for Di Francesco's men, whose recent games against Monza across Serie A, Serie B and the Coppa Italia have resulted in one win in six, with four losses and a draw.
A draw could be on the cards given the Biancorossi's seemingly diminished motivation and Frosinone's historical struggles in this fixture.
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Udinese vs. Empoli (Sunday, 2.00pm)
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With a win sufficient to secure their Serie A survival, Udinese host fellow relegation battlers Empoli in a crucial Sunday showdown.
After taking five points from three games, the Friulani can defy the drop by beating their Tuscan counterparts, who sit just one point behind in the standings.
We say: Udinese 1-0 Empoli
As Empoli do not travel well, Udinese should register just a second home win of the season; after previously staring into the abyss, the Bianconeri can clinch safety with one game to spare, partly thanks to Fabio Cannavaro's calming influence.
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Inter Milan vs. Lazio (Sunday, 5.00pm)
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Playing their final home fixture of a stellar Serie A season, champions Inter Milan welcome Lazio to San Siro on Sunday evening.
While Inter have long since secured a 20th Scudetto and can afford to take their foot off the gas, their visitors from the capital are aiming to seal a spot in Europe for next season.
We say: Inter Milan 2-1 Lazio
With the hard work done, Inter have little left to play for, but they hold a proud home record and will be keen to avoid defeat against in-form Lazio.
Back to full strength, the champions should be able to unpick their visitors' improving defence, taking them closer to a club-record points total.
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Roma vs. Genoa (Sunday, 7.45pm)
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After suffering back-to-back blows in Serie A and Europe, Roma aim to claim victory in their final home fixture of the season, as they welcome Genoa to Stadio Olimpico on Sunday.
The Giallorossi's hopes of returning to the Champions League are hanging by a thread, while their Ligurian counterparts have not given up on securing a top-half finish.
We say: Roma 2-2 Genoa
Roma's revival under Daniele De Rossi - who recently extended his short-term contract by three years - has started to falter, so plucky Genoa could leave the capital with a point.
The Grifone never know when they are beaten, and they possess sufficient firepower to test their hosts' increasingly leaky defence.