Arturo Vidal and Douglas Costa are poised to make their first Bundesliga appearances for Bayern Munich against Hamburger SV following their summer moves to the club.
Lahm starts at right-back over Rafinha, who starts on the bench alongside Mario Gotze and new signing Joshua Kimmich.
Emir Spahic and Albin Ekdal are set to make their debut appearances for the visitors, as will forwards Sven Schlipplock and Michael Gregoritsch.
Pierre-Michel Lasogga starts on a six-man bench for Hamburger.
Bayern Munich: Neuer; Lahm, Boateng, Benatia, Alaba; Vidal, Alonso; Robben, Muller, Costa; Lewandowski
Subs: Ulreich, Thiago, Rafinha, Bernat, Gotze, Kimmich, Hojbjerg
Hamburger SV: Adler; Diekmeier, Djourou, Spahic, Ostrozolek; Ekdal, Jung, Holtby; Gregoritsch, Schipplock, Ilicevic
Subs: Hirzel, Kacar, Muller, Lasogga, Olic, Diaz
Stephen Topping
