Atletico Madrid manager Diego Simeone has made three changes to the side that won 1-0 at home to Espanyol, with captain Gabi returning in place of the injured Tiago against Granada.
Simeone welcomes his captain back into a three-man midfield that also contains Koke and Saul Niguez.
Atletico's front three is where the other two changes are made, as Yannick Carrasco and Fernando Torres replace Luciano Vietto and Oliver Torres.
Torres and Carrasco are joined in the Madrid attack by the team's top scorer Antoine Griezmann, who scored his sixth league goal in the win over Espanyol.
Granada are without the suspended Javi Marquez, who is replaced in midfield by Ruben Perez.
Granada: Fernandez; Lomban, Biraghi, Rico, Babin; El Arabi, Perez, Success, Foulquier, Rochina; Penaranda
Subs: Kelava, Mainz, Rober, Piti, Neuton, Uche, Lopez
Atletico Madrid: Oblak; Juanfran, Godin, Gimenez, Luis; Níguez, Gabi, Koke; Carrasco, Torres, Griezmann
Subs: Moya, Gamez, Savic, Thomas, Oliver, Correa, Vietto
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