A blockbuster battle that could make or break Arsenal's Premier League title chances awaits on Wednesday night, as the Gunners visit the Etihad Stadium to face reigning champions Manchester City.

Mikel Arteta's men dropped points for the third game running on Friday night, playing out a spectacular 3-3 draw with basement side Southampton as Martin Odegaard and Bukayo Saka restored parity in the dying embers.

The North London club's destiny is still in their own hands as they hold a five-point lead over Pep Guardiola's men, which would be extended to eight with victory in Manchester, but the champions have two games in hand.

Here, Sports Mole rounds up Arsenal's latest injury and suspension news ahead of their clash with Man City, who cruised past Sheffield United 3-0 in Saturday's FA Cup semi-final.

Mohamed Elneny

Mohamed Elneny celebrates scoring for Arsenal against Oxford United on January 9, 2023 © Reuters

Status: Out
Type of injury: Knee
Possible return date: Unknown

Experienced midfielder Mohamed Elneny picked up a severe knee injury towards the end of January, and the Egypt international will sit out the rest of the season after undergoing surgery.

Takehiro Tomiyasu

Arsenal's Takehiro Tomiyasu comes off injured on March 16, 2023 © Reuters

Status: Out
Type of injury: Knee
Possible return date: Unknown

As is the case with Elneny, Takehiro Tomiyasu has been rendered unavailable for the remainder of the campaign, having undergone his own operation to address the knee problem that he sustained against Sporting Lisbon in the Europa League.

William Saliba

Arsenal's William Saliba goes down injured on March 16, 2023 © Reuters

Status: Out
Type of injury: Back
Possible return date: Unknown

Gooners across the globe have been awaiting positive news on William Saliba's back injury with bated breath, but Arteta admitted before the Southampton draw that the centre-back was not progressing as quickly as the club had hoped, and he will miss Wednesday's game in a devastating blow for the Gunners.

Granit Xhaka

Status: Minor doubt
Type of injury: Illness
Possible return date: April 26 (vs. Man City)

Granit Xhaka was a late withdrawal from the squad to face Southampton on Friday due to illness, but the Switzerland captain is expected to recover in time for the trip to Manchester.