Gloucester Rugby can overtake Northampton Saints in the Aviva Premiership table on Saturday if they beat their hosts at Franklin's Gardens.
The West Country club, who are in sixth place in the table, come into the match with one win in their last three league games.
Fifth-placed Northampton have fared even worse in recent weeks, losing three out of four matches.
The hosts have made wholesale changes as they welcome the returns of Ken Pisi, George Pisi, Stephen Myler and Lee Dickson.
Gloucester have named six news faces in their starting XV, with Nick Wood and Jonny May among those included.
Recent form
Northampton: LWWLWL
Gloucester: LLWWLL
Lineups
Northampton: Wilson, K Pisi, G Pisi, Waldouck, Elliott, Myler, Dickson, Tonga'uiha, Haywood, Mercey, Manoa, Sorenson, Dowson, Nutley, Van Velze
Replacements: McMillan, Waller, Doran Jones, Craig, Oakley, Roberts, Lamb, May
Gloucester: Cook, Sharples, Tindall, Molenaar, May, Mills, Robson, Wood, Dawidiuk, Harden, Lokotui, James, Savage, Qera, Kalamafoni
Replacements: d'Apice, Murphy, Thomas, Buxton, Cox, Cowan, Monahan, Thomas
Sports Mole says: Northampton to snatch the spoils
Jack Prescott
