Sale Sharks have confirmed that James Gaskell and Henry Thomas will leave the club at the end of the season.
Back-row Gaskell is expected to join London Wasps in the summer, while prop Thomas has been linked with a move to Bath.
"We're confident that we'll replace the lads and we wish them all the best," director of rugby Steve Diamond told the club's official website.
"It's the nature of the beast that while some players want to stay, others wish to move on. There's no rancor or bad feeling and we'll wish both of the lads good luck when they do move on."
Gaskell joined Sale in 2008, two years before Thomas arrived at the club.