As Serie A's supreme leaders Napoli seek a place in the Champions League quarter-finals on Wednesday, when they host Eintracht Frankfurt at Stadio Maradona, they have a number of fitness concerns to consider.

The Partenopei start the second leg of their last-16 tie with a 2-0 lead, but in addition to Giacomo Raspadori's confirmed absence with a thigh injury they picked up a couple of injuries to key players last weekend.

First-choice goalkeeper Alex Meret withdrew from the XI to face Atalanta on Saturday after sustaining an injury in the warm-up, while Kim Min-jae came off nursing a calf problem. Both have returned to training, however, so should still start.

Stand-in stopper Pierluigi Gollini will return to the bench if Meret is cleared to play, but Matteo Politano should keep his place on the right wing despite Hirving Lozano potentially overcoming his muscular issue.

One man definitely available to Luciano Spalletti again is full-back Mario Rui, who has served a two-match domestic suspension over the past fortnight.

The Portugal international is therefore set to replace Mathias Olivera on the left side of the hosts' back four, while captain Giovanni Di Lorenzo - who scored the second goal in Frankfurt last month - lines up on the right.

As ever, top scorer Victor Osimhen starts up front, supported from the flank by Khvicha Kvaratskhelia. The latter's wondergoal opened the scoring against Atalanta, continuing a rich vein of form for the 22-year-old winger.

Napoli possible starting lineup: Meret; Di Lorenzo, Kim, Rrahmani, Rui; Anguissa, Lobotka, Zielinski; Politano, Osimhen, Kvaratskhelia

> Click here to see how Eintracht Frankfurt could line up for this Champions League contest