Manchester United could reportedly be without their first-choice full-backs Luke Shaw and Aaron Wan-Bissaka until after the November international break.
Shaw has been absent since suffering a muscular injury during his side's second match of the 2023-24 Premier League campaign against Tottenham Hotspur.
Wan-Bissaka, meanwhile, picked up a hamstring problem during the league contest with Brighton & Hove Albion last weekend, which saw him miss out against Bayern Munich in the Champions League.
Man United have not given timeframes when it comes to either player, but according to The Mirror, the duo could be absent until after the November international break.
The Red Devils will take on Luton Town in the league on November 11 before returning to action on November 25 against Everton, which could mark the return of Shaw and Wan-Bissaka to the squad.
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Shaw's injury led to Man United signing Sergio Reguilon on loan from Tottenham Hotspur in the closing stages of the summer transfer window.
Tyrell Malacia is Shaw's back-up at left-back, but the Netherlands international has not played this season due to injury.
Reguilon has benefited from the absentees to start Man United's last two matches, and he is again expected to be in the XI against Burnley in the Premier League on Saturday evening.
Diogo Dalot, meanwhile, is set to continue at right-back at Turf Moor, with the 20-time English champions currently short of options in the full-back areas.
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Man United could be handed a huge injury boost for the game with Burnley, though, as Raphael Varane, Mason Mount, Harry Maguire and Sofyan Amrabat could all potentially be in the squad.
Amrabat is yet to make his debut for the Red Devils after arriving on loan from Fiorentina earlier this month, but he is in contention for this weekend's contest.
A disastrous start to the season has seen Man United lose four of their opening six games in all competitions, including a 4-3 defeat to Bayern in the Champions League on Wednesday.
Erik ten Hag's side have picked up just six points from their five league games, meanwhile, which has left them in 13th position in the table ahead of the next set of matches.
Jadon Sancho will again be missing against Burnley, as the forward is still not being considered for selection due to his fall-out with Ten Hag.
