Manchester United will welcome FA Cup holders Arsenal to Old Trafford in the quarter-finals of the competition, while Liverpool will host Blackburn Rovers in the sixth round.
England manager Roy Hodgson made the draw at Deepdale on Monday evening, ahead of the last-16 tie between Preston North End and the Red Devils.
Louis van Gaal's charges beat the Lilywhites 3-1 to secure a home tie against Arsenal, with both sides looking to become the first team to win the Cup for a 12th time.
The other two ties see giant-killers Bradford City rewarded with another home game against Reading, while local rivals Aston Villa and West Bromwich Albion will do battle.
FA Cup quarter-final draw:
Liverpool vs. Blackburn Rovers
Bradford City vs. Reading
Manchester United vs. Arsenal
Aston Villa vs. West Bromwich Albion
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