Manchester City will start with the Argentinian strike pairing of Carlos Tevez and Sergio Aguero against Wigan on Saturday.
Tevez, who City manager Roberto Mancini confirmed was no longer captain on Friday, will make his first Premier League start of the season.
He replaces in-form Edin Dzeko, who has netted six times so far this season - more goals than 16 of the 20 Premier League teams.
For the Latics James McArthur starts in place of Jordi Gomez, who drops to the bench.
Manchester City: Hart; Richards, Kompany, Lescott, Clichy; Silva, Johnson, Milner, Y Toure; Tevez, Aguero
Wigan Athletic: Al Habsi; Caldwell, Boyce, Piscu, Figueroa; Watson, Moses, McArthur, Diame; Di Santo, Rodallega