Lazio head into Sunday's fixture with Fiorentina looking to maintain their slender lead over their opponents as they attempt to move into third position in the Serie A table.
Both Biancazzurri and Viola are fighting for the final Champions League spot currently occupied by Napoli, and a win for either side could see them overtake their rivals should Rafael Benitez's team lose against Inter Milan.
Lazio have benefited from no European action, with three successive victories being recorded to extend their current run to 12 points from six games.
Goalkeeper Federico Marchetti may return after missing out in the Coppa Italia against Napoli in midweek, while Miroslav Klose could retain his place after netting in the same game.
Fiorentina travel to the Stadio Olimpico unbeaten in 13 games in all competitions and Vincenzo Montella will have confidence in his side that they can record their eighth league win on the road this season.
Over the past 10 days, Fiorentina have progressed to the last 16 of the Europa League as well as registering back-to-back wins on the road against Inter Milan and Juventus.
After making changes for the Coppa Italia in midweek, Montella is likely to revert back to the team that beat Inter, but Mohamed Salah is pushing hard for a recall.
The on-loan Chelsea winger has been a revelation since arriving in Italy, netting six goals in seven fixtures, with five coming in his last four outings.
Lazio:
Form in Serie A: WLLWWW
Form in all competitions: LLWWWD
Possible starting lineup: Marchetti; Basta, de Vrij, Mauricio, Radu; Cataldi, Biglia, Parolo; Candreva, Klose, Felipe Anderson
Fiorentina:
Form in Serie A: DDWWDW
Form in all competitions: WDDWWW
Possible starting lineup: Neto, Rodriguez, Pasqual, Tomovic, Savic, Aquilani, Ilicic, Badelj, Kurtic, Diamanti, Babacar
Sports Mole says: 1-1
No Data Analysis info