Mick McCarthy has handed Guirane N'Daw a start for Ipswich Town having limped off with cramp during their 5-0 defeat to Crystal Palace during the week.
Paul Taylor misses out with a foot injury while Lee Martin is suspended.
Ben Mee is only deemed fit enough for a place among the substitutes having struggled with a foot injury.
Chris McCann starts having completed 90 minutes against Leeds United in midweek.
Ipswich Town: Henderson; Cresswell, Chambers, Higginbotham, Smith; Edwards, N'daw, Wellens, Reo-Coker; Campbell, Murphy
Subs: Loach, Hewitt, Bilel, Emmanuel-Thomas, Drury, Chopra, Scotland
Burnley: Grant; Trippier, Lafferty, Duff, Shackell; McCann, Wallace, Marney, Stock; Paterson, Austin
Subs: Jensen, Edgar, Mee, Stanislas, Bartley, Vokes, Ings