The 25-year-old became a doubt for Steve Kean's side when he picked up the injury in a 2-1 victory over AEK Athens on Sunday.
The newly-demoted Championship club confirmed the fate of the frontman today following a scan on his knee.
Best moved to Ewood Park from Newcastle United earlier this month.
Restore Data
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Leeds UnitedLeeds | 42 | 25 | 13 | 4 | 82 | 29 | 53 | 88 |
| 2 | Burnley | 42 | 24 | 16 | 2 | 57 | 13 | 44 | 88 |
| 3 | Sheffield UnitedSheff Utd | 42 | 26 | 7 | 9 | 57 | 33 | 24 | 83 |
| 4 | Sunderland | 42 | 21 | 13 | 8 | 57 | 38 | 19 | 76 |
| 5 | Bristol City | 42 | 16 | 16 | 10 | 54 | 45 | 9 | 64 |
| 6 | Coventry CityCoventry | 41 | 18 | 8 | 15 | 58 | 53 | 5 | 62 |
| 7 | West Bromwich AlbionWest Brom | 42 | 14 | 18 | 10 | 51 | 39 | 12 | 60 |
| 8 | Middlesbrough | 42 | 17 | 9 | 16 | 61 | 51 | 10 | 60 |
| 9 | Millwall | 42 | 16 | 12 | 14 | 41 | 41 | 0 | 60 |
| 10 | Blackburn RoversBlackburn | 42 | 16 | 8 | 18 | 45 | 45 | 0 | 56 |
| 11 | Watford | 42 | 16 | 8 | 18 | 50 | 55 | -5 | 56 |
| 12 | Swansea CitySwansea | 42 | 15 | 9 | 18 | 45 | 51 | -6 | 54 |
| 13 | Norwich CityNorwich | 42 | 13 | 14 | 15 | 63 | 58 | 5 | 53 |
| 14 | Sheffield WednesdaySheff Weds | 42 | 14 | 11 | 17 | 56 | 64 | -8 | 53 |
| 15 | Queens Park RangersQPR | 42 | 12 | 14 | 16 | 49 | 55 | -6 | 50 |
| 16 | Preston North EndPreston | 42 | 10 | 19 | 13 | 43 | 51 | -8 | 49 |
| 17 | Oxford UnitedOxford Utd | 42 | 12 | 12 | 18 | 43 | 60 | -17 | 48 |
| 18 | Stoke CityStoke | 42 | 11 | 14 | 17 | 43 | 54 | -11 | 47 |
| 19 | Portsmouth | 42 | 12 | 10 | 20 | 50 | 66 | -16 | 46 |
| 20 | Hull City | 41 | 11 | 11 | 19 | 40 | 49 | -9 | 44 |
| 21 | Derby CountyDerby | 42 | 11 | 10 | 21 | 44 | 54 | -10 | 43 |
| 22 | Cardiff CityCardiff | 42 | 9 | 15 | 18 | 45 | 66 | -21 | 42 |
| 23 | Luton TownLuton | 42 | 10 | 10 | 22 | 37 | 63 | -26 | 40 |
| 24 | Plymouth ArgylePlymouth | 42 | 9 | 13 | 20 | 44 | 82 | -38 | 40 |
| > Championship Full Table | |||||||||
