Arsenal vs. Southampton (Wednesday, 6.00pm)
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Out-of-form Arsenal will be looking to ease the pressure on under-fire manager Mikel Arteta when they welcome high-flying Southampton to the Emirates Stadium on Wednesday evening.
The Gunners go into their 13th match of the campaign sitting 15th in the table, just five points above the relegation zone, whereas Southampton climbed into the top four with a comfortable victory over Sheffield United at the weekend.
We say: Arsenal 0-1 Southampton
Southampton may never get a better chance to end their woeful away record against Arsenal than this match, with the Gunners in disarray and struggling to pick up a point or even score a goal at the Emirates right now.
Arteta's side still have the quality to turn that dreadful form around this season, but it will be a big ask for them to do that against an in-form Southampton side full of confidence at the moment.
Our tipster partners are predicting a double chance bet on a home win or an away win.
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> How Arsenal could line up against Southampton
> Arsenal injury, suspension list vs. Southampton
Leeds vs. Newcastle (Wednesday, 6.00pm)
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Two teams in contrasting form face off at Elland Road on Wednesday evening as Leeds United play host to Newcastle United.
Leeds have lost back-to-back games to slip down to 14th, while Newcastle are now three points better off than their opponents thanks to rare successive victories.
We say: Leeds United 1-1 Newcastle United
This is the first Premier League meeting between the sides since January 2004 and it is Newcastle who enter the game in better form.
Leeds have struggled to hold onto leads in recent games and are slipping down the division, though they did remain unbeaten in all 14 of their midweek games in the Championship last season.
Not since November 2018 have Newcastle won three top-flight games in a row, meanwhile, and we can see that wait going on a little longer come the end of this contest.
Our tipster partners are predicting under 3.5 goals.
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Leicester vs. Everton (Wednesday, 6.00pm)
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Leicester City welcome Everton to the King Power Stadium on Wednesday evening sitting just one point adrift of Premier League leaders Tottenham Hotspur.
However, the Toffees remain just four points adrift of their hosts after recording an impressive 1-0 victory over Chelsea at the weekend.
We say: Leicester City 2-1 Everton
While few would have given Everton much of a chance a few weeks ago, it is a different story after the Toffees got the better of Chelsea. Nevertheless, Leicester have seemingly rediscovered their groove at both ends of the pitch, and we are backing the Foxes to prevail in a competitive match.
Our tipster partners are predicting a double chance bet on a home win or an away win.
> Click here to read our full preview for this match
Fulham vs. Brighton (Wednesday, 8.00pm)
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Fulham play host to Brighton & Hove Albion on Wednesday evening knowing that victory will move them outside of the Premier League relegation zone.
Meanwhile, the Seagulls make the trip to Craven Cottage on the back of a 3-0 defeat at Leicester City, a result which has left the club just two points above the bottom three.
We say: Fulham 2-1 Brighton & Hove Albion
Potter will be confident that his side will not be outclassed in the same fashion as Sunday evening. Nevertheless, Fulham are enjoying their most productive period of the campaign, and we fancy Parker's side to edge out their opponents in a hard-fought battle in West London.
Our tipster partners are predicting under 3.5 goals.
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West Ham vs. Crystal Palace (Wednesday, 8.00pm)
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West Ham United take on London rivals Crystal Palace on Wednesday evening with a chance to climb into the Premier League's top four.
The Hammers have been in fine form of late and are just three points outside the Champions League spots, while opponents Palace are three points back in 11th.
We say: West Ham United 2-1 Crystal Palace
West Ham lost 3-1 to Man United last time out at the London Stadium, but that was their first home defeat in seven matches in all competitions, winning five of those.
Palace have a rather mixed record on their travels, beating Fulham and West Brom either side of defeats to Wolverhampton Wanderers and Burnley without scoring.
Ultimately, though, United have been the more consistent side so far this season and we can see them edging this midweek London derby.
Our tipster partners are predicting under 3.5 goals.
> Click here to read our full preview for this match
Liverpool vs. Spurs (Wednesday, 8.00pm)
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Christmas will come early for Premier League fans when the champions host the leaders in a mouth-watering midweek showdown as Liverpool welcome Tottenham Hotspur to Anfield on Wednesday night.
The two sides are separated by only goal difference heading into the contest, but both will be looking to bounce back from underwhelming 1-1 draws at the weekend.
We say: Liverpool 1-1 Tottenham Hotspur
While this promises to be a fascinating contest, that does not necessarily mean that it will be a thriller and Mourinho will no doubt set up to soak up pressure before looking to hit Liverpool's depleted backline on the break - something they are capable of doing to devastating effect.
It would not be too much of a surprise to therefore see Spurs end Liverpool's long home unbeaten run here, but it is nigh-on impossible to back against the Reds at Anfield right now. Klopp's side seem to get the job done time after time on home territory, so we are sitting on the fence and predicting a draw here.
Our tipster partners are predicting under 3.5 goals.
> Click here to read our full preview for this match
> How Spurs could line up against Liverpool
> How Liverpool could line up against Tottenham
> Spurs injury, suspension list vs. Liverpool
