Venus Williams has pulled out of the US Open due to illness.
The two-time champion was scheduled to play Wimbledon semi-finalist Sabine Lisicki in their second-round match, but withdrew after being diagnosed with autoimmune disease.
The 31-year-old has already pulled out from two hard court tournaments over the summer with a virus.
Lisicki will now face either Slovakia's Dominika Cibulkova or the USA's Irina Falconi in round three.
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